Basic Information
VIS ID
TVIS44032663
Fusion event
HTLV-1-NEPRO integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q13.2
Reference genome
NCBI36/hg18
Start
114220333/113018796 (Hg38)
End
114220333/113018796 (Hg38)
Orient
+
Location type
Intronic
Target gene
NEPRO
miRNAs that regulate target gene
hsa-mir-28-3p ; hsa-mir-4451 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-4650-3p ; hsa-mir-3614-5p ; hsa-mir-1255b-2-3p
Nearest miRNA
hsa-let-7g/Upstream/281615; hsa-mir-12124/Downstream/413322;
Nearest TSS
ENST00000440867/Upstream/7260; ENST00000470313/Downstream/364;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/27373, chr3-CpG: 48/Downstream/601
Upstream sequence
ATTCataacagcttccatttgagtgttcatttaccatgccaggcagtgttccaaatgctttctctacattatcaactctttcatccccccaaacagccct
Downstream sequence
atgaggaaggtgcttttatctccatttgaaagtgagatcagtgaggcacagaaaggttcaatgactccttcaagctccagcaaagggtagagctagtatt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate