Basic Information
VIS ID
TVIS44032673
Fusion event
HTLV-1-SLC10A3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
q28
Reference genome
NCBI36/hg18
Start
153371229/154489696 (Hg38)
End
153371229/154489696 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRAXE ; FRAXF
Target gene
SLC10A3
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-26b-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-mir-185-3p ; hsa-mir-4283 ; hsa-mir-4489 ; hsa-mir-8075 ; hsa-mir-4656 ; hsa-mir-4502 ; hsa-mir-4731-5p ; hsa-mir-122-5p ; hsa-mir-1237-5p ; hsa-mir-1290 ; hsa-mir-130a-3p ; hsa-mir-146a-5p ; hsa-mir-146b-5p ; hsa-mir-153-3p ; hsa-mir-1909-5p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3151-5p ; hsa-mir-3165 ; hsa-mir-3167 ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-4303 ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4488 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4505 ; hsa-mir-454-3p ; hsa-mir-4671-3p ; hsa-mir-4682 ; hsa-mir-4697-5p ; hsa-mir-4762-3p ; hsa-mir-491-5p ; hsa-mir-5001-5p ; hsa-mir-504-3p ; hsa-mir-574-5p ; hsa-mir-5787 ; hsa-mir-589-5p ; hsa-mir-6076 ; hsa-mir-6742-5p ; hsa-mir-6796-5p ; hsa-mir-6797-3p ; hsa-mir-6846-5p ; hsa-mir-6848-5p ; hsa-mir-6880-5p ; hsa-mir-7153-5p ; hsa-mir-762 ; hsa-mir-8071 ; hsa-mir-876-5p ; hsa-mir-9-5p
Nearest miRNA
hsa-let-7f-2/Upstream/39310; hsa-mir-1184-1/Downstream/278900;
Nearest TSS
ENST00000429181/Upstream/3026; ENST00000492469/Downstream/918;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2660, chrX-CpG: 74/Downstream/619
Upstream sequence
AGTGTTTCTAGCGGCCAGCAACACCCCCTTCCACTTCTCAATCTGGGCAGCGACCACCGTAGTGTCACATCACCTGCTAGAACTGGGGCAACCAGGATGG
Downstream sequence
AGACACAACAGCTTTACATCACCCCTGTCAGTTGCCTCATGCACTGTTGTGTCCCAGTCCTAGAAGAGGACTGCCTCTATAGATCCTATCCGTCTTTGGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate