Basic Information
VIS ID
TVIS44032676
Fusion event
HTLV-1-SHB integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
p13.1
Reference genome
NCBI36/hg18
Start
37991936/38001939 (Hg38)
End
37991936/38001939 (Hg38)
Orient
-
Location type
Intronic
Target gene
SHB
miRNAs that regulate target gene
hsa-mir-935 ; hsa-mir-939-5p ; hsa-mir-6826-3p ; hsa-mir-7160-5p ; hsa-mir-6778-3p ; hsa-mir-6089 ; hsa-mir-5008-5p ; hsa-mir-4649-3p ; hsa-mir-1234-3p ; hsa-mir-7107-5p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-4308 ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-7113-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-4469 ; hsa-mir-6868-3p ; hsa-mir-212-5p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-660-3p ; hsa-mir-5193
Nearest miRNA
hsa-mir-101-2/Upstream/1108408; hsa-let-7a-1/Downstream/2927071;
Nearest TSS
ENST00000422679/Upstream/97586; ENST00000422554/Downstream/66748;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/97461, chr9-CpG: 248/Downstream/65747
Upstream sequence
ACCTCTGTAGATAACAGCCCAAAGGAGATGAACAGGAGAGAAGAGAAAAGGCCATCTGCATCCTCCCCATGAGCTCCAGAGAGCACGAGTGGTGGTGAGT
Downstream sequence
GACTTTCATCCACCCTGATCCCACCTCACAGGACCTGGCTCTGAGCACAGACTCTTTTTAATGGAAGGGAGGGGAAGGGGACAGGGACTGATGTGATATA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate