Basic Information
VIS ID
TVIS44032688
Fusion event
HTLV-1-CDC42BPA integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q42.13
Reference genome
NCBI36/hg18
Start
225397949/227143625 (Hg38)
End
225397949/227143625 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
CDC42BPA
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-let-7c-5p ; hsa-mir-485-5p ; hsa-mir-218-5p ; hsa-mir-4753-3p ; hsa-mir-6868-3p ; hsa-mir-1468-3p ; hsa-mir-3124-3p ; hsa-mir-130b-5p ; hsa-mir-8063 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-216b-5p ; hsa-mir-4311
Nearest miRNA
hsa-mir-101-1/Upstream/1221483; hsa-mir-1182/Downstream/797965;
Nearest TSS
ENST00000473358/Upstream/30826; ENST00000424451/Downstream/34708;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/167089, chr1-CpG: 104/Downstream/174120
Upstream sequence
tgtatgtgattcactgcttgcaaaggctcccaagcatagtgctgaagcgctgtctagtgttcctagcgccagaggacagtgatgtgcctttatggagaaa
Downstream sequence
ataatgtgctagaaaagcttcattcaggcacgagttacagtgctgctggtggtgagttcagtggtgagttcagtgttaatgaatcaacaacatatgttat
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate