Basic Information
VIS ID
TVIS44032721
Fusion event
HTLV-1-NRG3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q23.1
Reference genome
NCBI36/hg18
Start
84712160/82962424 (Hg38)
End
84712160/82962424 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
NRG3
Nearest miRNA
hsa-mir-1265/Upstream/7409871; hsa-mir-107/Downstream/3302270;
Nearest TSS
ENST00000439456/Upstream/162682; ENST00000372134/Downstream/713015;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1086451, chr10-CpG: 24/Downstream/602519
Upstream sequence
TAGGGATCAGAAAAGAAAGTCATCAAAAGAGATCATCCGTTCTTCTCTCTTAAAATCAAGAGAAAATATTCACAATTGAAAAATGAAAGAAGAAAATTGT
Downstream sequence
ATACCCTTCATACCTTTTTTTTCAGTAATCATTTTAAGAAAGGTAAGTTTATGGGGGAGGTAACATTAAATGAGAAAGAACTGGAAGATAATACTTGCAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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