Basic Information
VIS ID
TVIS44032722
Fusion event
HTLV-1-MRPS30 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
p12
Reference genome
NCBI36/hg18
Start
44845660/44809801 (Hg38)
End
44845660/44809801 (Hg38)
Orient
-
Location type
Intronic
Target gene
MRPS30
miRNAs that regulate target gene
hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-548s ; hsa-mir-5696 ; hsa-mir-3926 ; hsa-mir-570-3p ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-4729 ; hsa-mir-665 ; hsa-mir-1273e ; hsa-mir-6771-5p ; hsa-mir-4722-5p ; hsa-mir-7160-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-7153-5p ; hsa-mir-1827 ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-4649-3p ; hsa-mir-6746-5p ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-548n
Nearest miRNA
hsa-mir-10397/Upstream/6252240; hsa-mir-103a-1/Downstream/9141703;
Nearest TSS
ENST00000502646/Upstream/876; ENST00000508129/Downstream/42;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/211, chr5-CpG: 100/Downstream/885491
Upstream sequence
TGGCCTGGTTTTGTAACAGTCACTGCGTTAGGAATCTAGAGACTAGGTGTGTGTGGCTGCGCTAACACCTACCAGCTCTTCAACTCTGAAAGCCTGAGCT
Downstream sequence
CTCCAGGATTCCAGTCCTGGATTCTACTTTGTGAGTGTTCAGCCAAATGGAAGAGCAGTGGTGATGAAGAGAAACGCCACTTAAGAGAGTGGGGCGGGCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate