Basic Information
VIS ID
TVIS44032750
Fusion event
HTLV-1-TENM1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
q25
Reference genome
NCBI36/hg18
Start
123957704/124996174 (Hg38)
End
123957704/124996174 (Hg38)
Orient
+
Location type
Intronic
Target gene
TENM1
miRNAs that regulate target gene
hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-3653-3p ; hsa-mir-3658 ; hsa-mir-4778-3p ; hsa-mir-4698 ; hsa-mir-5680 ; hsa-mir-7154-5p ; hsa-mir-8060 ; hsa-mir-335-3p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-6516-3p ; hsa-mir-4536-5p ; hsa-mir-6876-3p ; hsa-mir-626 ; hsa-mir-215-3p
Nearest miRNA
hsa-let-7f-2/Upstream/3625121; hsa-mir-105-1/Downstream/9173204;
Nearest TSS
ENST00000429181/Upstream/32357; ENST00000632600/Downstream/323946;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/662827, chrX-CpG: 17/Downstream/206747
Upstream sequence
TTATGGAAGGTTTTTATTTTAAACCAATAAGTGGACTTTTAATAGTGAAATCTGAGAATTGTGCATATTCTTTAGAAAATCCAAGTTATAATCCTGAAGT
Downstream sequence
ACTATAATCATCTAATAGGTGCCTGATCTTTCAAATTCTTTAATCCTTCTTCACATTAACTTTCTGACCTAGCTTTTTGCAAACACTCCTAAGTCCCTGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate