VISDB - VIS Detail

Basic Information

VIS ID

TVIS44032778

Fusion event

HTLV-1-KIAA1328 integration

Validated

Detection method

HTS

Data source

Curated

Sample type

Nontumor

Disease

Not given

Quality evaluation

Normal

Reported year

2019

PubMed ID

30307560

Virus Sequence

Virus name

HTLV-1

Subtype

HTLV-1c

Reference genome

KF242506

Host Sequence

Chromosome

chr18

Cytoband

q12.2

Reference genome

NCBI36/hg18

Start

32811607/36977646 (Hg38)

End

32811607/36977646 (Hg38)

Orient

Location type

Intronic

Fragile sites / regions

FRA18A

Target gene

KIAA1328

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7162-3p ; hsa-mir-544b ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-1288-5p ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-3714 ; hsa-mir-665 ; hsa-mir-6741-5p ; hsa-mir-6514-3p ; hsa-mir-6771-5p ; hsa-mir-7977 ; hsa-mir-6748-5p ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-7160-5p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6746-5p ; hsa-mir-5690 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6888-5p

Nearest miRNA

hsa-mir-1-2/Upstream/1043504; hsa-mir-122/Downstream/679489;

Nearest TSS

ENST00000575820/Upstream/53706; ENST00000586501/Downstream/89220;

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/148320, chr18-CpG: 28/Downstream/266189

Upstream sequence

TCTCAGATAATTTGTCTGAGTACTCAGGGCACTATCTCATAGAGAAGGACACCCAACTGGAACTGTGTGCCACCCTAACGTCATTTTTTTGTTTTTAAAA

Downstream sequence

CAAGGGACCACATTAATCAAACCCAGAAACAAGGTGTTTCAgggttctcaagacaacccccaggtttagtgattgacaagactcagaaggctctgcatat

Reference

Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.