Basic Information
VIS ID
TVIS44032786
Fusion event
HTLV-1-HIVEP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q24.2
Reference genome
NCBI36/hg18
Start
143293584/142930754 (Hg38)
End
143293584/142930754 (Hg38)
Orient
+
Location type
Intronic
Target gene
HIVEP2
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-130b-3p ; hsa-mir-598-3p ; hsa-mir-484 ; hsa-mir-10b-5p ; hsa-mir-136-5p ; hsa-mir-298 ; hsa-mir-5684 ; hsa-mir-5700 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4662a-3p ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-302c-3p ; hsa-mir-372-3p ; hsa-mir-520e ; hsa-mir-520b ; hsa-mir-373-3p ; hsa-mir-520a-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p
Nearest miRNA
hsa-mir-10398/Upstream/2246871; hsa-mir-1202/Downstream/8171921;
Nearest TSS
ENST00000381078/Upstream/93707; ENST00000417650/Downstream/14277;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/3453, chr6-CpG: 279/Downstream/13828
Upstream sequence
ATTTACATAGTACTCAAGTGTTTGAGAGCACATCTCCTTGTTCAGCCTCCATCTATATTAAATACTTCAGAATAGGCCCTCAATGAAATCTAAGTAATAG
Downstream sequence
TTAAGTACTCAGATGGCCTATAATCAAGCATGTTATTGAAACAGCAGTGTCCCCACATGAATTCAAGTAAAACAAAATTATTTTTTATTACAATATAGTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate