Basic Information
VIS ID
TVIS44032826
Fusion event
HTLV-1-CTNNA2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
NCBI36/hg18
Start
80555469/80474833 (Hg38)
End
80555469/80474833 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
CTNNA2
Nearest miRNA
hsa-mir-1285-2/Upstream/608250; hsa-mir-10b/Downstream/5308767;
Nearest TSS
ENST00000437798/Upstream/96146; ENST00000467892/Downstream/114506;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/152160, chr2-CpG: 93/Downstream/719247
Nearest cancer related gene
CTNNA2(TSG, No orient, 0)
Upstream sequence
AGACAGGCTGGTTAGATAGCTACTTGGAAGTGTTGACAGGAAATTAAATTTGCAAACAGAAATAAAACCGTGGTAGAATTTTTGAATACAAGGACAAAAG
Downstream sequence
CAAGGAAATTGAATATTGAGATTATTTGTAGCATTCTTCCCTGGGGATGGAGAATTGAAGAGCACATGGTTTGCCATTCATCGGAAGGTCAAACCCAAGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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