Basic Information
VIS ID
TVIS44032829
Fusion event
HTLV-1-CSGALNACT1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
NCBI36/hg18
Start
19401502/19499711 (Hg38)
End
19401502/19499711 (Hg38)
Orient
+
Location type
Intronic
Target gene
CSGALNACT1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-126-5p ; hsa-mir-16-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-124-5p ; hsa-mir-616-3p ; hsa-mir-627-3p ; hsa-mir-3925-3p ; hsa-mir-1825 ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-4255 ; hsa-mir-199a-5p ; hsa-mir-199b-5p ; hsa-mir-765 ; hsa-mir-3663-3p ; hsa-mir-4786-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-3620-3p ; hsa-mir-6871-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-124-1/Upstream/1818054; hsa-mir-10400/Downstream/2745255;
Nearest TSS
ENST00000518652/Upstream/4520; ENST00000519803/Downstream/32309;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/37967, chr8-CpG: 27/Downstream/102683
Upstream sequence
ATCTGCCCCAGTCCATGGTCAAAAGAGCTGGTCCTCATCAAAGTTATCAGGAATGTACTGTGAGACTCATAATTCCATGTTCCTTTTCCTTGACCTCTCC
Downstream sequence
CTTCTGTCCCCTCCACCTCGGAGGTaggaccagctacacagtttgcagggcccagtgtaaaatgaaaatgtggggccccttaaacatgattaagaatgtc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate