Basic Information
VIS ID
TVIS44032843
Fusion event
HTLV-1-NPAS3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q13.1
Reference genome
NCBI36/hg18
Start
32856250/33317293 (Hg38)
End
32856250/33317293 (Hg38)
Orient
-
Location type
Intronic
Target gene
NPAS3
miRNAs that regulate target gene
hsa-mir-17-5p ; hsa-mir-3679-3p ; hsa-mir-4446-5p ; hsa-mir-361-3p ; hsa-mir-153-5p ; hsa-mir-589-3p ; hsa-mir-548as-3p ; hsa-mir-143-5p ; hsa-mir-2681-5p ; hsa-mir-3944-5p ; hsa-mir-8066
Nearest miRNA
hsa-mir-208a/Upstream/2302551; hsa-mir-1185-1/Downstream/3635016;
Nearest TSS
ENST00000550708/Upstream/101981; ENST00000552696/Downstream/242892;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/377264, chr14-CpG: 152/Downstream/482447
Upstream sequence
AGTGCTATTAATGATTGAATAACATTAGCTTTTCCATGGCAGAAGTATTTCATCACAGCACATGTTCAGAGCACATAtaccctctattaggcactatact
Downstream sequence
gagtgctttcgtggtactgttttcttctagtgatcccaactctatgaagtaggcattcttattatcccactttacagatgagtaaaccaaggcttaccaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate