Basic Information
VIS ID
TVIS44032857
Fusion event
HTLV-1-DDAH1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p22.3
Reference genome
NCBI36/hg18
Start
85670247/85431976 (Hg38)
End
85670247/85431976 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
DDAH1
miRNAs that regulate target gene
hsa-mir-210-3p ; hsa-mir-30b-5p ; hsa-mir-34a-5p ; hsa-mir-21-5p ; hsa-mir-18a-3p ; hsa-mir-221-3p ; hsa-mir-100-5p ; hsa-mir-92a-3p ; hsa-mir-18a-5p ; hsa-mir-1261 ; hsa-mir-5096 ; hsa-mir-377-3p ; hsa-mir-4775 ; hsa-mir-196a-3p ; hsa-mir-3128 ; hsa-mir-1228-3p ; hsa-mir-892b ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-590-3p ; hsa-mir-6509-5p ; hsa-mir-374b-3p ; hsa-mir-331-5p ; hsa-mir-4766-3p ; hsa-mir-140-3p ; hsa-mir-548p ; hsa-mir-411-5p ; hsa-mir-585-5p ; hsa-mir-891a-3p ; hsa-mir-376a-2-5p ; hsa-mir-5693 ; hsa-mir-936 ; hsa-mir-30e-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-mir-128-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-29b-2-5p ; hsa-mir-376c-5p ; hsa-mir-376b-5p ; hsa-mir-509-3p ; hsa-mir-759 ; hsa-mir-6849-5p ; hsa-mir-4797-5p ; hsa-mir-3681-5p ; hsa-mir-3910 ; hsa-mir-548an ; hsa-mir-182-5p ; hsa-mir-183-5p ; hsa-mir-1271-5p ; hsa-mir-96-5p ; hsa-mir-5696 ; hsa-mir-4729 ; hsa-mir-579-3p ; hsa-mir-664b-3p
Nearest miRNA
hsa-mir-101-1/Upstream/298103; hsa-mir-11399/Downstream/925656;
Nearest TSS
ENST00000473358/Upstream/27448; ENST00000610230/Downstream/33164;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/155124, chr1-CpG: 145/Downstream/32281
Upstream sequence
GAAATTAATACAAGAGGCAGGATCTCAGAGCATGATAATTTCCCACAACCTCAGGCACCTGATCTATGCTAACATACCAAATGAGTACAATCTAATGTTA
Downstream sequence
ACACAAACATGATGAGCTTTACAGTTAAATATTTTGTTAACTCCTAAATACAATAAAAGGGATTTCTAAAAGAACCTCAGGAAACACGTGGTAACTTTGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate