Basic Information
VIS ID
TVIS44032865
Fusion event
HTLV-1-ELP3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p21.1
Reference genome
NCBI36/hg18
Start
28023920/28110484 (Hg38)
End
28023920/28110484 (Hg38)
Orient
-
Location type
Intronic
Target gene
ELP3
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-342-5p ; hsa-mir-193b-3p ; hsa-mir-3934-3p ; hsa-mir-3664-3p ; hsa-mir-1324 ; hsa-mir-4524b-3p ; hsa-mir-4684-5p ; hsa-mir-3675-3p ; hsa-mir-5583-3p ; hsa-mir-6771-3p ; hsa-mir-548c-3p ; hsa-mir-4786-5p ; hsa-mir-7162-3p ; hsa-mir-544b ; hsa-mir-6849-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-4293
Nearest miRNA
hsa-mir-124-1/Upstream/224368; hsa-mir-10400/Downstream/394632;
Nearest TSS
ENST00000518652/Upstream/10646; ENST00000520011/Downstream/8414;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/17133, chr8-CpG: 160/Downstream/274916
Upstream sequence
GCTATCCGTGCCAGATATGACCCTTTCCTACAGACAAGACACCGAATAGAACAGGTACATTTTTAAAAAACATGTTTCTTAAAAATTAGGTGTTTATACT
Downstream sequence
TAGTAAGAAGCCATTGTTGCTTGATTCAAATTGAACCTGAAATAAGAATGAAAAAGGTGTTTTTCCTCTTTGTAAGTTTTCAATATCCATTTGAGGGAGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate