Basic Information
VIS ID
TVIS44032871
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
NCBI36/hg18
Start
68406354/68168083 (Hg38)
End
68406354/68168083 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
GNG12-AS1 ; WLS
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-let-7b-5p ; hsa-mir-186-5p ; hsa-mir-3682-3p ; hsa-mir-331-5p ; hsa-mir-6793-3p ; hsa-mir-4678
Nearest miRNA
hsa-mir-101-1/Upstream/1539566; hsa-mir-11399/Downstream/15435;
Nearest TSS
ENST00000473358/Upstream/12899; ENST00000425820/Downstream/8294;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/4564, chr1-CpG: 83/Downstream/62842
Upstream sequence
AGTCTGTCTCTATACCAGTTATACTGCCCTGCCCTGCTTGAGAAAAGCAAAGCCAATCAGTTTTTCTGCAGGCAAGTGGAAAGTCAGAGAGGAGGGCAAG
Downstream sequence
TACCTTCTATAAGCCAGAAATGGTGGGAGGGGGGTGCTAGAAATCGCTAGGAAAGAGGTCTAGTGTCCCCAAGAAATCTAGGGCAGCTGCTTAATGTAAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate