Basic Information
VIS ID
TVIS44032882
Fusion event
HTLV-1-LRRC63 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q14.13
Reference genome
NCBI36/hg18
Start
45714979/46242843 (Hg38)
End
45714979/46242843 (Hg38)
Orient
+
Location type
Intronic
Target gene
LRRC63
miRNAs that regulate target gene
hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-1277-5p ; hsa-mir-561-3p ; hsa-mir-548at-5p
Nearest miRNA
hsa-mir-2276/Upstream/2046643; hsa-mir-1267/Downstream/3753572;
Nearest TSS
ENST00000623511/Upstream/29808; ENST00000612699/Downstream/55001;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/189959, chr13-CpG: 93/Downstream/143706
Upstream sequence
taggagagagtgttgaagaaaaaaaaaaaacaaaaaacctctcaactgagactactatacccattaaagtgtctcttcaaacacaaaggagagataaaga
Downstream sequence
ctttccccaaataacaaaagatgaaggaattcataaacaccaaacctgtccaaaaaaatgctacagggagtccttccatctggaagaaatggaccctaag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate