Basic Information
VIS ID
TVIS44033007
Fusion event
HTLV-1-FKBP15 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q32
Reference genome
NCBI36/hg18
Start
115023326/113221225 (Hg38)
End
115023326/113221225 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA9E
Target gene
FKBP15
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-615-3p ; hsa-mir-151a-3p ; hsa-mir-4448 ; hsa-mir-3670 ; hsa-mir-6857-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-4463 ; hsa-mir-4499 ; hsa-mir-6842-3p ; hsa-mir-647 ; hsa-mir-3678-3p ; hsa-mir-1273h-3p ; hsa-mir-548aw ; hsa-mir-3162-5p ; hsa-mir-1273g-5p ; hsa-mir-203a-5p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4687-3p ; hsa-mir-7974 ; hsa-mir-3202 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6823-5p ; hsa-mir-8063 ; hsa-mir-296-3p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-5584-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-500a-3p ; hsa-mir-2467-3p ; hsa-mir-3121-5p ; hsa-mir-3919 ; hsa-mir-6782-3p
Nearest miRNA
hsa-let-7a-1/Upstream/1289056; hsa-mir-12126/Downstream/988209;
Nearest TSS
ENST00000422679/Upstream/13929; ENST00000496650/Downstream/54;
Nearest CpG islands
chr9-CpG: 60/Target, None/Upstream, None/Downstream
Upstream sequence
CCCCTCCAACAATCCGCCGGTATCTCTCAGCCACGCCCTCCAGCGCATACTTCTCAGTCACTCACCCGCCGCTCGGCGAGAGGAAATCGGTGTCGTCCTC
Downstream sequence
GTCCCCCGCACCGAACATTGCGTTGGCTTTCACCGGGTTGCGGGGAGGAAGCTGGGTATTCCCAGAGTCCCAGGGCCTGTCACCGCCGACGTCGTAAAAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate