Basic Information
VIS ID
TVIS44033011
Fusion event
HTLV-1-AMZ1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p22.3
Reference genome
NCBI36/hg18
Start
2686053/2679893 (Hg38)
End
2686053/2679893 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7B
Target gene
AMZ1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-186-5p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-877-3p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-324-5p ; hsa-mir-4304 ; hsa-mir-4469 ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-1470
Nearest miRNA
hsa-mir-339/Upstream/152748; hsa-mir-10399/Downstream/2108672;
Nearest TSS
ENST00000635602/Upstream/371; ENST00000480560/Downstream/8309;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/403, chr7-CpG: 91/Downstream/8155
Upstream sequence
CTGGGCAAAGGCCAGGAGACCAGGGAAGAAAGGACAGAGTCTGGAGCCCGGGAGAGGTGGCGAGGGGCCATAGCCCTGAAGGAGCTTCATCCTGGGGCTT
Downstream sequence
CATCCGAGTTGAGGAGGCCCAGCTGGGGGTGAAGGGTGCCTCGTAGGCAGAGGGACCCCGGAGGTAGGAACTAGGGATGTGAGGCTGGGGCAGACAGAGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate