Basic Information
VIS ID
TVIS44033023
Fusion event
HTLV-1-MARCH8 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q11.22
Reference genome
NCBI36/hg18
Start
45407624/45592170 (Hg38)
End
45407624/45592170 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
MARCH8
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1265/Upstream/428082; hsa-mir-107/Downstream/3393342;
Nearest TSS
ENST00000439456/Upstream/56776; ENST00000485850/Downstream/2321;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/147939, chr10-CpG: 65/Downstream/2253
Upstream sequence
AGTCACATCATCAACCTGGCTCTCCAAACACACCAAATTTTTTGTTGACTATTGATTTAAAAAATGAATTAGAAAATTCAGGCATTTCCAAGTGAGTTAA
Downstream sequence
GAAATTGGTCTGGACAAGAAAGAAAGAAAGAGTTTAAAATTACACTCCTTGAAAAAGAATTTCAAAATTGAAAACCCTTCAATACAGCAAAGACAAAGCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate