Basic Information
VIS ID
TVIS44033031
Fusion event
HTLV-1-NUDT4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q22
Reference genome
NCBI36/hg18
Start
92300731/93382824 (Hg38)
End
92300731/93382824 (Hg38)
Orient
+
Location type
Intronic
Target gene
NUDT4
miRNAs that regulate target gene
hsa-let-7f-5p ; hsa-let-7a-5p ; hsa-mir-548c-3p ; hsa-mir-361-3p ; hsa-mir-153-5p ; hsa-mir-6818-3p ; hsa-mir-4684-5p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-3185 ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-339-5p ; hsa-mir-8060 ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-6732-3p
Nearest miRNA
hsa-let-7i/Upstream/6637675; hsa-mir-1178/Downstream/1178965;
Nearest TSS
ENST00000382841/Upstream/4170; ENST00000548545/Downstream/24499;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/4405, chr12-CpG: 139/Downstream/58335
Upstream sequence
ggagtgcagtggcgcgatgtcagcttactgcaagctccgccttccaggttcacgccattctcaagtagctgggactacaggcagccgccaccatacctgg
Downstream sequence
ctaattttttgtatttttagtagagaaggggtttcactgtgttagccaggatggtcttgatctcctgaccttgtgatttacccacctcagcctcccaaag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate