Basic Information
VIS ID
TVIS44033032
Fusion event
HTLV-1-ARL13B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q11.2
Reference genome
NCBI36/hg18
Start
95206237/94004703 (Hg38)
End
95206237/94004703 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARL13B
miRNAs that regulate target gene
hsa-mir-106b-5p ; hsa-mir-132-3p ; hsa-mir-1266-3p ; hsa-mir-1277-5p ; hsa-mir-944 ; hsa-mir-5585-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-4502 ; hsa-mir-7849-3p ; hsa-mir-5692a ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-3149 ; hsa-mir-568 ; hsa-mir-8068 ; hsa-mir-6516-3p ; hsa-mir-1206 ; hsa-mir-5000-5p
Nearest miRNA
hsa-let-7g/Upstream/6778426; hsa-mir-12124/Downstream/2355261;
Nearest TSS
ENST00000440867/Upstream/24415; ENST00000477077/Downstream/23907;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/24114, chr3-CpG: 36/Downstream/58101
Upstream sequence
TTGTTCTTGTGGTTCATTATTAAGGATTAAAAAAAAAAAAAATCAACCTGTCATGTGGTTAGATGAAAAATTGTAGAGTTTCTCAGTGGTCTTCAGTAGT
Downstream sequence
AAATGAACATTTTTAAATGAGGTGGTTTGGAAGCTCTGATTGCAAAAGTTAAAACTGTATTATATAATTTATTGCTAAAGTTGATACttttaaattttta
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate