Basic Information
VIS ID
TVIS44033057
Fusion event
HTLV-1-PALM integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
NCBI36/hg18
Start
672065/721065 (Hg38)
End
672065/721065 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
PALM
miRNAs that regulate target gene
hsa-mir-324-5p ; hsa-mir-6818-3p ; hsa-mir-6873-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-7107-3p ; hsa-mir-6753-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-6753-5p ; hsa-mir-1911-3p
Nearest miRNA
hsa-mir-1302-11/Upstream/648955; hsa-let-7e/Downstream/83875;
Nearest TSS
ENST00000633603/Upstream/1965; ENST00000586776/Downstream/1439;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/112, chr19-CpG: 20/Downstream/6891
Upstream sequence
GCTGGAAACCAGGACTGTGGGGTGGCCCGGGGCTGGGCGGTTGTTGTTCCAATCTGGCTGTGCCCAGGGCCACGCTGTGCCCTCCCTGGACGTGGCTTCC
Downstream sequence
AGCCATGGGAAGAAGGTGCCGGGCAGGGGGAACCGTGTGTGAGAGGCCCTGGGGTAGGAGGCTTGGTGCATAGCCAGGGGGCCCTGCAGGAGTAGACCAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate