Basic Information
VIS ID
TVIS44033079
Fusion event
HTLV-1-DNM2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
NCBI36/hg18
Start
10794402/10822726 (Hg38)
End
10794402/10822726 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
DNM2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-130a-3p ; hsa-mir-615-3p ; hsa-mir-92a-3p ; hsa-mir-6875-5p ; hsa-mir-6809-5p ; hsa-mir-765 ; hsa-mir-711 ; hsa-mir-4784 ; hsa-mir-4708-3p ; hsa-mir-3150b-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4761-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125
Nearest miRNA
hsa-mir-1181/Upstream/5230; hsa-let-7e/Downstream/6247;
Nearest TSS
ENST00000633603/Upstream/13518; ENST00000589106/Downstream/498;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/104062, chr19-CpG: 70/Downstream/13114
Upstream sequence
tagctgggattacaggcatgcagtaccactcccagctaattttttgtattttagtattgacggggtttcaccatgttggccaggctggtctcaaactcct
Downstream sequence
gacctcagttgatcctcctgcctcagcttcccaaagtgttgggattacaggcgtgagccactgtgcccagccAAAACTTTTTTTATAAAAAACACACAgg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate