Basic Information
VIS ID
TVIS44033082
Fusion event
HTLV-1-RHOT1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
NCBI36/hg18
Start
27496440/32145308 (Hg38)
End
27496440/32145308 (Hg38)
Orient
+
Location type
Intronic
Target gene
RHOT1
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-335-5p ; hsa-mir-877-3p ; hsa-mir-139-5p
Nearest miRNA
hsa-mir-1180/Upstream/569787; hsa-mir-10226/Downstream/204801;
Nearest TSS
ENST00000595228/Upstream/2173; ENST00000581567/Downstream/57516;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/2385, chr17-CpG: 197/Downstream/120267
Upstream sequence
agaatggctttcacccaggagatggaggtcgcagtgagctgagatcacaccactgcattccaacctgggggacagagtgagactctgtctcaaaaaaTAT
Downstream sequence
ATATATATATTGATAATAGTAAACAGGATAGTTTTCATTTTAATGGAGTCTTCTTTTTAAATTAAATTGAGATATATTTGTTTTCTACTAGTTAAGTTCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate