Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene164928826164555584164899296164705848164709653164699355164702866164725154164727043164703125164704969164722475164724224164711536164713260164731022164732285164735519164736498164716725164717599164719000164719400164733184164733333164742205
Basic Information
VIS ID
TVIS44033091
Fusion event
HTLV-1-PBX1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
NCBI36/hg18
Start
162978066/164742205 (Hg38)
End
162978066/164742205 (Hg38)
Orient
-
Location type
Intronic
Target gene
PBX1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-21-5p ; hsa-mir-877-3p ; hsa-mir-149-5p ; hsa-mir-196b-5p ; hsa-mir-198 ; hsa-mir-1247-3p ; hsa-mir-3074-5p ; hsa-mir-4722-3p ; hsa-mir-617 ; hsa-mir-6505-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6882-3p
Nearest miRNA
hsa-mir-101-1/Upstream/2399565; hsa-mir-1182/Downstream/1165716;
Nearest TSS
ENST00000473358/Upstream/90309; ENST00000559560/Downstream/30707;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/165525, chr1-CpG: 29/Downstream/375314
Nearest cancer related gene
PBX1(OG, No orient, 0)
Upstream sequence
TACCTCTTGAGAAACTGCAGATTAGGGAAACCTGTAGATATTTTATTCTATCTCAGGTAGGGAAAGACAAGCCTTCAAAGGCTTTTAATGACAGGGTATC
Downstream sequence
TGTATTACTTACGGATTGGAAGGCCCATCATGTATTCAATATCAAGGATCACAAagccaggagtggtggctcacgcctgtaatcccagcactttgtgagg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate