Basic Information
VIS ID
TVIS44033094
Fusion event
HTLV-1-FAT1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q35.2
Reference genome
NCBI36/hg18
Start
187750143/186591995 (Hg38)
End
187750143/186591995 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAT1
miRNAs that regulate target gene
hsa-mir-125b-5p ; hsa-mir-222-3p ; hsa-mir-181a-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-12113/Upstream/1653555;
Nearest TSS
ENST00000502981/Upstream/36428; ENST00000507644/Downstream/3750;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/36305, chr4-CpG: 327/Downstream/131170
Nearest cancer related gene
FAT1(TSG, No orient, 0)
Upstream sequence
TCGATGGCCTCTGTAagcagttctcgagtgggatctctagaccggcaccatcagagctacctgggaactggtgaaaaatgcaaattctaaagtcccaacc
Downstream sequence
cagacctgttggatcagaaatgctggtgctgagaaccagcaattgggcttttaacagccctccagatgatctgattcacattacagtttgaaaagtactA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate