VISDB Viral Integration Site DataBase

VIS ID

TVIS44033120

Fusion event

HTLV-1-AURKA integration

Validated

No

Detection method

HTS

Data source

Curated

Sample type

Disease

Not given

Quality evaluation

Normal

Reported year

2019

PubMed ID

Virus name

HTLV-1

Subtype

HTLV-1c

Reference genome

Chromosome

chr20

Cytoband

q13.2

Reference genome

Start

End

54382217/56373754 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-193a-3p ; hsa-mir-3918 ; hsa-mir-3127-5p ; hsa-mir-137 ; hsa-mir-4448 ; hsa-mir-6736-3p ; hsa-mir-154-5p ; hsa-mir-7843-5p ; hsa-mir-6735-5p ; hsa-mir-6879-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-92b-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-7152-5p ; hsa-mir-4326 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-885-3p ; hsa-mir-149-5p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-183-5p ; hsa-mir-8076 ; hsa-mir-6779-3p ; hsa-mir-578 ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-4721 ; hsa-mir-3616-3p ; hsa-mir-581 ; hsa-mir-129-1-3p ; hsa-mir-1290 ; hsa-mir-1914-5p ; hsa-mir-3152-5p ; hsa-mir-3167 ; hsa-mir-3611 ; hsa-mir-378j ; hsa-mir-4755-3p ; hsa-mir-4774-3p ; hsa-mir-4782-5p ; hsa-mir-518c-5p ; hsa-mir-5706 ; hsa-mir-660-3p ; hsa-mir-6778-3p ; hsa-mir-6791-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-6839-5p ; hsa-mir-760 ; hsa-mir-876-5p

Nearest miRNA

hsa-mir-103a-2/Upstream/2305269; hsa-mir-1-1/Downstream/947748;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/14440, chr20-CpG: 75/Downstream/18226

Nearest cancer related gene

AURKA(OG, No orient, 0)

Upstream sequence

GGTTTGCAGGTTTTggccaggcacagtggctcacacctataatcccaacactttgggggactgaggtgggaggatcacttgagcccaggggttcaagacc

Downstream sequence

agcctgggaaacatagcaagactccatctctacaaaaatttaaaaattagctgagcgtgatggtgcatgcctgtagtcccagctacttgggaggctgagg