Basic Information
VIS ID
TVIS44033122
Fusion event
HTLV-1-ETFA integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q24.2
Reference genome
NCBI36/hg18
Start
74329189/76249793 (Hg38)
End
74329189/76249793 (Hg38)
Orient
-
Location type
Intronic
Target gene
ETFA
miRNAs that regulate target gene
hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-18a-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-10393/Upstream/487478; hsa-mir-11181/Downstream/2959995;
Nearest TSS
ENST00000557528/Upstream/18395; ENST00000558437/Downstream/34048;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/57554, chr15-CpG: 51/Downstream/61429
Upstream sequence
gcctcccaaagtgctgggattacaggtgtgagccaccatgcccggcccagtaatcattttaaaatatatagttctgggacactaagtacagttaccttgt
Downstream sequence
tatgcaaccatcaccacccatcttcagaactACCGCCTATCTCAAGAACTGCAAAAGTTTTTTTAAAACTGTAAATAAGCAAAGTTCAGAGAGCTGTTAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate