Basic Information
VIS ID
TVIS44033124
Fusion event
HTLV-1-LDAH integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p24.1
Reference genome
NCBI36/hg18
Start
20851963/20788722 (Hg38)
End
20851963/20788722 (Hg38)
Orient
-
Location type
Intronic
Target gene
LDAH
miRNAs that regulate target gene
hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-21-5p
Nearest miRNA
hsa-mir-3125/Upstream/1440217; hsa-mir-10b/Downstream/4539918;
Nearest TSS
ENST00000437798/Upstream/48731; ENST00000447260/Downstream/34367;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/117202, chr2-CpG: 30/Downstream/34082
Upstream sequence
AAGATGCTCATACCACTAGAGAGACGTACAAGAACCAGAAGCAAACTGGGCAATGAAGTCACAGCCACCTCGATCTCACCTCAAATTAACTAAAGGAAAC
Downstream sequence
CCCCTAGGACAAAACGCCCTTGAATGGAATGCCTATAGAGCATTCCAATTGTTACACCTTTTGAAAGTGTCCTTCAACTCTTGGATATGCTGTACTTTTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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