Basic Information
VIS ID
TVIS44033128
Fusion event
HTLV-1-INTS11 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
NCBI36/hg18
Start
1243729/1318486 (Hg38)
End
1243729/1318486 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
INTS11
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-1226-3p ; hsa-mir-320a ; hsa-mir-23b-3p
Nearest miRNA
hsa-mir-12136/Upstream/5920; hsa-mir-101-1/Downstream/21164;
Nearest TSS
ENST00000473358/Upstream/1036; ENST00000488011/Downstream/860;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/5373, chr1-CpG: 18/Downstream/456
Upstream sequence
gtgactcatgcctgtaatccgagcactttgagaggctgaggtgggaggatccctggagcccagcccaggagttcgagagccttagcaacacatacccatc
Downstream sequence
tctacaaaaaataccaaaataaattagctgggcgtatgggcacatgcttgtagtcccagctacttgggaggccgaggtgggagatcacctcaacccggga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate