Basic Information
VIS ID
TVIS44033134
Fusion event
HTLV-1-AHCTF1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
NCBI36/hg18
Start
245100123/246870198 (Hg38)
End
245100123/246870198 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1I
Target gene
AHCTF1
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-186-5p
Nearest miRNA
hsa-mir-101-1/Upstream/3523943; hsa-mir-3124/Downstream/331769;
Nearest TSS
ENST00000473358/Upstream/5900; ENST00000474792/Downstream/6870;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/80989, chr1-CpG: 144/Downstream/60985
Upstream sequence
tggagaaaacaactgcagatatgggggaaagagcaagagaactagaatgagaagcagagcctaggccaggcatgatggctcatgcctgtaatcccagtac
Downstream sequence
ttttggaggccaaggtgggaggatcacttgaggccatgagtttgagaatagcctgggcgacatagtgaggccctctctacaaaaaatacccaggcacggt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate