Basic Information
VIS ID
TVIS44033150
Fusion event
HTLV-1-VTI1A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q25.2
Reference genome
NCBI36/hg18
Start
114446168/112696419 (Hg38)
End
114446168/112696419 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
VTI1A
miRNAs that regulate target gene
hsa-mir-18a-3p ; hsa-mir-18b-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-6891-3p ; hsa-mir-452-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-302a-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-205-5p ; hsa-mir-6793-3p ; hsa-mir-532-5p ; hsa-mir-141-5p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-107/Upstream/62165; hsa-mir-202/Downstream/1081574;
Nearest TSS
ENST00000439456/Upstream/18600; ENST00000346198/Downstream/253831;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/248857, chr10-CpG: 34/Downstream/253471
Upstream sequence
GATTTTCTCCTAACCAGTGAAATTTACAGAATGTTTTATAATTTTGGTAGCATAAGTCTTAATTCCTGAGGCTGGTTTGCATGCATTTCAAGACCAACCT
Downstream sequence
AAGTAAAATTGTTTCAGATTTCAGGATGTGTTTACTATTGATGGAATATAGATTGTCTACATTCTATATCCATTTTTGCTCTGTTACAAAGTAAAATGTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate