Basic Information
VIS ID
TVIS44033153
Fusion event
HTLV-1-SLC35F3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
NCBI36/hg18
Start
232266311/234063942 (Hg38)
End
232266311/234063942 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
SLC35F3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-101-1/Upstream/439723; hsa-mir-1537/Downstream/242525;
Nearest TSS
ENST00000473358/Upstream/159009; ENST00000366617/Downstream/150329;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/158231, chr1-CpG: 63/Downstream/150196
Upstream sequence
tttggcattcacctagaacttggcctcatcaacaggtagctaggaacgatctgagacctgccaatggccgcttcttctgtgaagatagtcctacatgtgg
Downstream sequence
gatctgagggtccagatagtcctgtattgttaactgcacctggaatgaaatctccatctcactgaactgTTTGTTTTTATAATTTCACCATTTTCACTGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate