Basic Information
VIS ID
TVIS44033183
Fusion event
HTLV-1-GRM3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q21.12
Reference genome
NCBI36/hg18
Start
86192281/86725029 (Hg38)
End
86192281/86725029 (Hg38)
Orient
-
Location type
Intronic
Target gene
GRM3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-487b-3p ; hsa-mir-129-5p ; hsa-mir-151a-3p ; hsa-mir-411-5p ; hsa-mir-4463 ; hsa-mir-4499 ; hsa-mir-4513 ; hsa-mir-6855-3p
Nearest miRNA
hsa-mir-10525/Upstream/10809760; hsa-mir-10399/Downstream/5478986;
Nearest TSS
ENST00000635602/Upstream/14930; ENST00000561473/Downstream/50993;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1538103, chr7-CpG: 45/Downstream/61275
Upstream sequence
TCCCACATCAAACAAACAAAAAAAATCTCCTGAGGTTTATTTAGGGTGATTTTGTGGAATTAAGGTGGATCCTGGACATTAGCATTACCAGATAATTCTT
Downstream sequence
ATCATTAGCCTGGAAACACTTCTTACTATTACCAGGGGATGTATgcattggagttgccaagaccttgatttgaatcctcattctttaatttcatggctat
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate