Basic Information
VIS ID
TVIS44033188
Fusion event
HTLV-1-UGP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p15
Reference genome
NCBI36/hg18
Start
63926724/63846086 (Hg38)
End
63926724/63846086 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
UGP2
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-193b-3p ; hsa-mir-32-5p ; hsa-mir-106b-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1301/Upstream/1640169; hsa-mir-10b/Downstream/494661;
Nearest TSS
ENST00000437798/Upstream/12; ENST00000465515/Downstream/8759;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/4314, chr2-CpG: 74/Downstream/172714
Upstream sequence
CACATCCCCAAGTCTCTGTCCCTCAGGCACTTAACATTCCTTCTCTTAGGAAGACCTTTCTTTACTGGATCTGCAGCATAATTCCTAGCTATTCTGCTGT
Downstream sequence
TGGGTCACCTTCTGCCTACTTGTGACATTCCTTCTGCTCTTCCTTGCTCCAGGGATTGTTCCAGGGCCCCCAGTTATTCTAAATGGATGTGAGTACCATC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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