Basic Information
VIS ID
TVIS44033195
Fusion event
HTLV-1-AGTR2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
q23
Reference genome
NCBI36/hg18
Start
115216577/116171296 (Hg38)
End
115216577/116171296 (Hg38)
Orient
+
Location type
Intronic
Target gene
AGTR2
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-142-3p ; hsa-mir-124-3p ; hsa-mir-5706 ; hsa-mir-4782-5p ; hsa-mir-516b-5p ; hsa-mir-1299 ; hsa-mir-1468-3p ; hsa-mir-6839-5p ; hsa-mir-378j ; hsa-mir-548p
Nearest miRNA
hsa-let-7f-2/Upstream/1347732; hsa-mir-105-1/Downstream/2215098;
Nearest TSS
ENST00000429181/Upstream/574; ENST00000463626/Downstream/265326;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/202232, chrX-CpG: 74/Downstream/1944974
Upstream sequence
AATAGTGTTTCCTTTGTATGCTTATCTTTAGCTAATGTGTTTTTTTTTTTGGTTTTAAAATAATGCTTCTAGTGAAAAAAATCACAAAAACCTCAACACT
Downstream sequence
GTAACGTTTGAGAGCAACGGCTATTCAGTTCGGTTAAACCGAAAAGAGAGAAAAAGAAAAATGATAAGACTATATCATGATTAATCATTGATGTTCATTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate