Basic Information
VIS ID
TVIS44033208
Fusion event
HTLV-1-SPATA21 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p36.13
Reference genome
NCBI36/hg18
Start
16627866/16428784 (Hg38)
End
16627866/16428784 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
SPATA21
miRNAs that regulate target gene
hsa-mir-498 ; hsa-mir-124-5p ; hsa-mir-4772-3p ; hsa-mir-1306-5p ; hsa-mir-1304-3p ; hsa-mir-6890-3p ; hsa-mir-6787-3p ; hsa-mir-6736-3p
Nearest miRNA
hsa-mir-12136/Upstream/3849761; hsa-mir-101-1/Downstream/430165;
Nearest TSS
ENST00000473358/Upstream/24810; ENST00000486390/Downstream/2587;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/61009, chr1-CpG: 70/Downstream/11719
Upstream sequence
ttttgatcactatcatggtctgtcactctccaactgggtgacctggagccagtgactgagaccccgctccaagcatcaCCGGAGTCAGCAAACTCCAAAC
Downstream sequence
AAATGGACTTAATTAACTCATTGACATTGATATAATACAAGATTCTGATGTGAGCtaatactaacaggcacctactatgagacagggcctgtgctaggtg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate