Basic Information
VIS ID
TVIS44033228
Fusion event
HTLV-1-KHDRBS2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q11.1
Reference genome
NCBI36/hg18
Start
62930041/62162177 (Hg38)
End
62930041/62162177 (Hg38)
Orient
+
Location type
Intronic
Target gene
KHDRBS2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-10398/Upstream/4771965; hsa-mir-10524/Downstream/9214783;
Nearest TSS
ENST00000381078/Upstream/1439029; ENST00000370659/Downstream/124050;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/4200627, chr6-CpG: 45/Downstream/123773
Upstream sequence
agtctctcaaatctgtagaaaataaaaaaatggagctacaaaccattgttaagataatactagcttttataattgctctttatttacctttattaagatc
Downstream sequence
tttatgtcttcatctggcttcaagttactgtctagtgtcttttaatttcaccctgaaggaccccctgaagcatttcttgcaaggaaggtctagtggcaat
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate