Basic Information
VIS ID
TVIS44033252
Fusion event
HTLV-1-LAMA2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q22.33
Reference genome
NCBI36/hg18
Start
129649865/129287027 (Hg38)
End
129649865/129287027 (Hg38)
Orient
-
Location type
Intronic
Target gene
LAMA2
miRNAs that regulate target gene
hsa-mir-580-3p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-539-5p ; hsa-mir-4511 ; hsa-mir-3133 ; hsa-mir-29b-3p ; hsa-mir-29a-3p
Nearest miRNA
hsa-mir-10398/Upstream/2802314; hsa-mir-1202/Downstream/2505145;
Nearest TSS
ENST00000381078/Upstream/403712; ENST00000645154/Downstream/4587;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/356853, chr6-CpG: 208/Downstream/732014
Upstream sequence
GTTTTTGGTaagaaagaaagagcaggagacaaagaaagaaagaaacagagaggaaggaaggaaggaagggaggaaagagggaaggagggagagagggagg
Downstream sequence
gagggagggaggaaggaaggaagcaaggaaggaaggaagggaggaaagagggagggagggaaggagggaaggagggaggaaggaaggaagagagagagag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate