Basic Information
VIS ID
TVIS44033264
Fusion event
HTLV-1-CHRM3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
NCBI36/hg18
Start
238045546/239815623 (Hg38)
End
238045546/239815623 (Hg38)
Orient
-
Location type
Intronic
Target gene
CHRM3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-296-3p ; hsa-mir-2467-3p ; hsa-mir-6878-5p ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-6856-5p ; hsa-mir-5197-3p ; hsa-mir-6758-5p ; hsa-mir-4311 ; hsa-mir-1277-5p ; hsa-mir-4776-3p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5590-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-5011-5p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-137 ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-670-5p ; hsa-mir-4445-5p ; hsa-mir-6766-3p ; hsa-mir-4782-3p ; hsa-mir-219a-5p ; hsa-mir-508-3p ; hsa-mir-339-5p ; hsa-mir-6079 ; hsa-mir-5186 ; hsa-mir-4522 ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-6888-5p ; hsa-mir-148a-5p ; hsa-mir-4428 ; hsa-mir-8075 ; hsa-mir-4728-3p
Nearest miRNA
hsa-mir-101-1/Upstream/2344432; hsa-mir-3123/Downstream/1316649;
Nearest TSS
ENST00000473358/Upstream/85158; ENST00000447095/Downstream/84249;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/427584, chr1-CpG: 105/Downstream/181914
Upstream sequence
CAGTAATTTAAACCAAGCATATAGTACAGTGGTTCTGAAAGCTTACATCTTGCAAAAAAGTAATTTGAAAATTTGAAAACAATAAGCTTATAGACTAAAG
Downstream sequence
CATAAAGAAAATGCCAGCACATTTACCACAGGGTAGGTCTAATTCAGCCTACTGGTAACCAACTCAAATGCAAAACAAAATGATAGCTGAACAATGAGCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate