Basic Information
VIS ID
TVIS44033306
Fusion event
HTLV-1-NDST1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q33.1
Reference genome
NCBI36/hg18
Start
149868632/150508877 (Hg38)
End
149868632/150508877 (Hg38)
Orient
-
Location type
Intronic
Target gene
NDST1
miRNAs that regulate target gene
hsa-mir-191-5p ; hsa-mir-375 ; hsa-mir-296-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-mir-24-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-4528 ; hsa-mir-5011-5p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-410-3p ; hsa-mir-5706 ; hsa-mir-4782-5p ; hsa-mir-516b-5p ; hsa-mir-1299 ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4638-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-1972 ; hsa-mir-1306-5p ; hsa-mir-4690-5p ; hsa-mir-216a-3p ; hsa-mir-3681-3p ; hsa-mir-128-3p
Nearest miRNA
hsa-mir-10397/Upstream/775987; hsa-mir-103a-1/Downstream/1013210;
Nearest TSS
ENST00000502646/Upstream/765; ENST00000624156/Downstream/41537;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/22367, chr5-CpG: 19/Downstream/19026
Upstream sequence
ACCACTCTGAATTTGTGTGTCTGGGGAGAGAATCTGCTAATAGCCATCATTAGATTCTCAAAGGGTTCTATAACCCCCAGAAGGTCACAGACTTCtcctc
Downstream sequence
tagtccatacccctcactgcagttgcagaaactgaggctcagagaagggaagggacttgcccagagactcacaggcggcaaTGGAGGCTGTGGCACCCCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate