Basic Information
VIS ID
TVIS44033311
Fusion event
HTLV-1-TENM4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
NCBI36/hg18
Start
78635984/79247291 (Hg38)
End
78635984/79247291 (Hg38)
Orient
+
Location type
Intronic
Target gene
TENM4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-193b-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-100-3p ; hsa-mir-3121-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-642a-5p ; hsa-mir-4290 ; hsa-mir-1236-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-6736-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-6826-3p ; hsa-mir-3925-3p ; hsa-mir-3667-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-622 ; hsa-mir-532-5p
Nearest miRNA
hsa-mir-10392/Upstream/3912105; hsa-let-7a-2/Downstream/154731;
Nearest TSS
ENST00000527297/Upstream/31382; ENST00000526154/Downstream/22382;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/177288, chr11-CpG: 292/Downstream/190023
Upstream sequence
agattacctgaggtcaggagattgagaccagcctggccaacatggtgaaaccccatctctactaaaaatacaaaaattagccgggcatggtggcaagtgc
Downstream sequence
ctgtgatcccagccactcaggaggctgaggcaggagaatcgcttgaatctgggaggcggaagttgcagtgagctgagatcacgccactgcattccagcct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate