Basic Information
VIS ID
TVIS44033313
Fusion event
HTLV-1-ST6GAL2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q12.3
Reference genome
NCBI36/hg18
Start
106803853/106820965 (Hg38)
End
106803853/106820965 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
ST6GAL2
miRNAs that regulate target gene
hsa-mir-5192 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-7153-5p ; hsa-mir-185-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-3925-5p ; hsa-mir-15b-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-125a-3p ; hsa-mir-3529-3p ; hsa-mir-552-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/4388599; hsa-mir-10b/Downstream/2320525;
Nearest TSS
ENST00000437798/Upstream/282886; ENST00000425419/Downstream/9114;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/333368, chr2-CpG: 39/Downstream/22102
Upstream sequence
catgaaaataaaatggtatgttcctgaatgaccagtggtccagtgaaaaaatttagaaaaaaaatttaaaagttccttgaaacaaatgatagtgaaaaca
Downstream sequence
caacataccaaaacctatgagataaagcaaaagtagtaccaagaggaaagtttatagctataagcatctacataaaaaagtagaacaacttcaagtaaac
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate