Basic Information
VIS ID
TVIS44033330
Fusion event
HTLV-1-TBC1D22A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr22
Cytoband
q13.31
Reference genome
NCBI36/hg18
Start
45685583/46911023 (Hg38)
End
45685583/46911023 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
TBC1D22A
miRNAs that regulate target gene
hsa-mir-342-5p ; hsa-mir-484 ; hsa-mir-4633-5p ; hsa-mir-532-5p ; hsa-mir-499b-3p ; hsa-mir-499a-3p ; hsa-mir-8485
Nearest miRNA
hsa-let-7a-3/Upstream/797255; hsa-mir-12114/Downstream/1363341;
Nearest TSS
ENST00000624155/Upstream/137096; ENST00000434707/Downstream/4885;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/50495, chr22-CpG: 19/Downstream/117295
Upstream sequence
AAGAATGCTGTAGCTCAGTGCAGCCACAATGTGGGTGCTGGCTGGGGAGACCCTGGGGCAGGGACCAGACTGAGGGGCCAGGGGTACTGCACTGGGGGTG
Downstream sequence
GTGGGGGCTCTGTCCGTGGGAGGTGAGGAGCATGCAGAGGTCTTCAGCCAGGTGTGCACATGTGCACGTGTATGGTGTGGGTGATAGGATTGTGTTGCAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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