Basic Information
VIS ID
TVIS44033333
Fusion event
HTLV-1-ADGRL2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
NCBI36/hg18
Start
81580006/81341733 (Hg38)
End
81580006/81341733 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
ADGRL2
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-455-3p ; hsa-mir-18a-3p ; hsa-let-7i-5p ; hsa-mir-221-3p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/4281531; hsa-mir-11399/Downstream/3792061;
Nearest TSS
ENST00000473358/Upstream/35534; ENST00000468283/Downstream/215969;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1010532, chr1-CpG: 281/Downstream/458580
Upstream sequence
TTTTTAAGCATTTTAATGGAAGTGATACTTAACGTTACTCTCATGTGACCATACAACCAGATGGTTCTACCTTTCTATAAAAACATGTTTGTAGAGCTCA
Downstream sequence
TTGGGAGTTACATATATTTGTGTATCTATGATGTACCTGCCTGCTAAAGCTCATCAACACTAATGAAGAATTAGTACCAATTACTCTAGTAAATGCTAGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate