Basic Information
VIS ID
TVIS44033341
Fusion event
HTLV-1-ZNF675 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
NCBI36/hg18
Start
23656383/23681741 (Hg38)
End
23656383/23681741 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF675
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-3976 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4279 ; hsa-mir-4502 ; hsa-mir-3921 ; hsa-mir-4653-5p ; hsa-mir-301b-5p ; hsa-mir-301a-5p ; hsa-mir-146a-3p ; hsa-mir-3675-3p ; hsa-mir-3927-5p ; hsa-mir-5694 ; hsa-mir-5571-5p ; hsa-mir-365b-3p ; hsa-mir-5583-5p ; hsa-mir-365a-3p ; hsa-mir-3129-3p ; hsa-mir-629-3p ; hsa-mir-183-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-4703-3p ; hsa-mir-600 ; hsa-mir-3925-3p ; hsa-mir-766-3p ; hsa-mir-4712-5p ; hsa-mir-770-5p ; hsa-mir-200b-5p ; hsa-mir-200a-5p ; hsa-mir-4653-3p ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-6514-5p
Nearest miRNA
hsa-mir-10395/Upstream/3282387; hsa-let-7e/Downstream/11440959;
Nearest TSS
ENST00000633603/Upstream/24607; ENST00000531821/Downstream/4640;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/210299, chr19-CpG: 21/Downstream/76697
Upstream sequence
agaccctgattcagagcacaatccacaacactgtctttactgcagatgccagtcacaaacttcatgggctgatctatgcttctgagccactgtttaataa
Downstream sequence
ctggggactcccagaactttcctcaagttcagtaatataacagagctattcacagaactcagtgaaacactgtagttatctttaccagtttattataaaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate