Basic Information
VIS ID
TVIS44033343
Fusion event
HTLV-1-PPP4R3B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
NCBI36/hg18
Start
55646702/55566062 (Hg38)
End
55646702/55566062 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
PPP4R3B
miRNAs that regulate target gene
hsa-mir-106b-5p ; hsa-mir-31-5p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-1301/Upstream/1716857; hsa-mir-10b/Downstream/416905;
Nearest TSS
ENST00000437798/Upstream/22042; ENST00000608113/Downstream/7656;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/46199, chr2-CpG: 79/Downstream/51069
Upstream sequence
TCTATTCCTATAGTCTTCCAATAGTATAATATCTGTGAAATAAACTAATTGATAGTAATAACTTCTAAATTCTAAACCATCACTGCAAATGCATGCATGC
Downstream sequence
CCAGTAGGCttattttaaaaaaaaaaattaaaGTTGTGATTGAGGACTTTACAGATAACACTACATAGTAAGAAACACACAGGTCATTTCTTGAAAAGAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate