Basic Information
VIS ID
TVIS44033344
Fusion event
HTLV-1-CEACAM21 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
NCBI36/hg18
Start
46756346/41558136 (Hg38)
End
46756346/41558136 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
CEACAM21
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10395/Upstream/1188229; hsa-let-7e/Downstream/311491;
Nearest TSS
ENST00000633603/Upstream/8616; ENST00000401445/Downstream/6546;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/35795, chr19-CpG: 28/Downstream/6861
Upstream sequence
TGAAATGGGGCCTATTTTCAGGCGATAAACAACTCTACAGAAAATGTGCCATTTTTATGCAATTCCTTTTTTCAGTGTTACTCTCCTACCTTTACAACTA
Downstream sequence
TTATATGCTCAAAGTTAAGCTAAGTTTCGTGGAAAACAGAAAACAAAATGCTTCATAATTATAAGTCATGAGATCTACATAGCATTTAAAATTTCTCTAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate