Basic Information
VIS ID
TVIS44033351
Fusion event
HTLV-1-MTMR6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q12.13
Reference genome
NCBI36/hg18
Start
24758093/25285955 (Hg38)
End
24758093/25285955 (Hg38)
Orient
-
Location type
Intronic
Target gene
MTMR6
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-15b-5p ; hsa-mir-190b ; hsa-mir-3611 ; hsa-mir-5189-3p ; hsa-mir-548q ; hsa-mir-548ax ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-302f ; hsa-mir-548aj-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-548n ; hsa-mir-943 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-6730-3p ; hsa-mir-7113-3p ; hsa-mir-6752-3p ; hsa-mir-1306-5p ; hsa-mir-888-3p
Nearest miRNA
hsa-mir-2276/Upstream/1123451; hsa-mir-1267/Downstream/14378079;
Nearest TSS
ENST00000623511/Upstream/24147; ENST00000481980/Downstream/2054;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/113966, chr13-CpG: 51/Downstream/1249
Upstream sequence
GCTATGCACCGTAGAAAGCATATGAAAAATAGAGGAGCTTCGAACTGATGCAGAAGGAAGTCACGTGCACTTAGCTACTACATAATACATATCTGGAACC
Downstream sequence
AATACAAGAACCTGATCCAATGTCCACTCTAGTCCTCTTTTCCTCTGTGCACCTTCTACGAGTTTGGTTATAGACTTAAGCACCCTTCCATTTTCAAAAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate