Basic Information
VIS ID
TVIS44033356
Fusion event
HTLV-1-ERCC2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
NCBI36/hg18
Start
50560767/45365669 (Hg38)
End
50560767/45365669 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ERCC2
miRNAs that regulate target gene
hsa-mir-1226-3p ; hsa-mir-17-5p ; hsa-mir-770-5p
Nearest miRNA
hsa-mir-10395/Upstream/606948; hsa-let-7e/Downstream/70985;
Nearest TSS
ENST00000633603/Upstream/1612; ENST00000590794/Downstream/4715;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/1565, chr19-CpG: 66/Downstream/4412
Upstream sequence
catagcactccagcctgggcgacagagtgagacaccatctcaaaaaaataagtaaaaataaaaatacaaaaatgagccaggtgtggtggtgcacacctgg
Downstream sequence
aatcccagctactcgggaggctgaggcaggagaatcccttgaacccagaaggcagaggttgcagtgagccgagatcatgccactgtactccaccctgggc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate